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KMID : 1040920210060020098
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Journal of Minimally Invasive Spine Surgery and Technique
2021 Volume.6 No. 2 p.98 ~ p.108
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Minimally Invasive Surgery vs. Open Surgery for Infectious Spondylodiscitis: A Systematic Review and Meta-Analysis
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Arimbawa Ida Bagus Gede
Wiguna I Gusti Lanang Ngurah Agung Artha
Savio Sherly Desnita
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Abstract
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Objective: Minimally Invasive Spinal (MIS) Procedure has long been used for treating degenerative spinal disorders, however its usage for infectious diseases of the spine has not been described a lot in literatures. Through this meta-analysis, we aim to objectively describe the efficacy of MIS as compared to traditional open surgery (OS) in treating infectious spondylodiscitis.
Methods: A systematic search was conducted based on PRISMA guideline to identify relevant studies through PubMed, Google Scholar, and Cochrane database. A total of 4 studies (301 patients) were included, divided into 8 meta-analysis, processed using Review Manager 5.3.
Results: OS requires significantly longer hospital length of stay (p=0.0009, I2=0%, MD=?6.64) and higher blood loss (p<0.00001, I2=40%, MD=?264.31) as well as more postoperative blood transfusion (p<0.00001, I2=0%, MD=?1.58). Moreover, MIS has benefit in significantly shorter operation time (p<0.00001, I2=46%, MD=?30.07) and less complication rate (p=0.0002, I2=38%, MD=0.32). However, the two procedures do not differ significantly in terms of neurological improvement, recurrence rate, and mortality rate.
Conclusion: Current systematic review and meta-analysis suggest that MIS offers comparable efficacy as well as less hospital length of stay, blood loss, operation time, and complication rate compared to OS.
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KEYWORD
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Meta-analysis, Minimally invasive surgery, Open surgery, Spondylodiscitis
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